- Genetic Embryo Testing
PGT-M Testing in Multan
PGT-M (Preimplantation Genetic Testing for Monogenic Disorders) screens embryos during IVF for a specific single-gene condition — such as thalassemia, cystic fibrosis, or sickle cell anaemia — so that only unaffected embryos are considered for transfer.
For families with a known inherited condition, this step offers real, evidence-based reassurance before pregnancy even begins, rather than uncertainty carried through to birth.
Thalassemia
Screened directly when either partner is a known carrier.
Cystic Fibrosis
A common single-gene disorder identified before transfer.
Sickle Cell Anaemia
Ruled out through the same targeted, single-gene screen.
- The Procedure
How PGT-M fits into your IVF cycle
PGT-M is carried out alongside the IVF cycle you’re already going through — one focused, condition-specific check before transfer.
1
IVF Cycle Starts
A standard IVF cycle begins as usual, with eggs retrieved and fertilised.
2
Embryo Biopsy
A small number of cells are carefully removed from each embryo.
3
Genetic Testing
Those cells are analysed for the specific condition being screened for.
4
Healthy Embryo Selection
Only embryos free of the condition are chosen for transfer.
- Why It Matters
Who should consider PGT-M testing
PGT-M is most valuable for couples facing a specific, identifiable genetic risk. It’s worth discussing with your fertility specialist if:
Family History
A known genetic disorder already runs in either partner's family.
Known Carrier Status
One or both partners carry a specific inherited condition.
A Previously Affected Child
A prior child was affected by the same genetic disease.
Unexplained Failure or Loss
Repeated IVF failure or recurrent miscarriage where a genetic cause is suspected.
- COMMON QUESTIONS
Frequently Asked Questions
It’s a test done during IVF that screens embryos for a specific single-gene disorder — such as thalassemia, cystic fibrosis, or sickle cell anaemia — before transfer.
It greatly reduces the risk of passing a known inherited condition to the next generation, giving prospective parents real reassurance before pregnancy.
A few cells are carefully removed from each embryo during IVF and analysed for the specific condition being screened for. Only unaffected embryos are chosen for transfer.
Couples with a known genetic disorder in the family, known carriers of an inherited condition, those who’ve previously had an affected child, or couples with repeated IVF failure or miscarriage where a genetic cause is suspected.
PGT-A screens embryos for chromosome-count abnormalities that can affect implantation or cause miscarriage. PGT-M instead tests for a specific, known inherited disorder caused by a single gene mutation.
PGT-M greatly reduces the risk of passing on the specific condition tested for, but it cannot guarantee a completely healthy baby, since pregnancy health depends on other factors too.
PGT-M is highly accurate at identifying the specific single-gene condition it’s designed to screen for.