- Understanding the Test
What Is Whole Exome Sequencing?
Whole Exome Sequencing (WES) is an advanced genetic test that examines the protein-coding regions of your DNA — the exome — where the majority of disease-linked mutations are found.
At Life IVF Multan, WES gives a comprehensive, efficient way to uncover the genetic basis of inherited conditions, going far beyond what traditional genetic tests can reveal. It has become a fundamental diagnostic tool in modern reproductive medicine.
Whether you’re planning a pregnancy, navigating recurrent loss, or going through IVF, WES gives you and your specialist detailed, actionable insight to guide treatment, prognosis, and family planning decisions.
WES at a Glance
- Checks for: mutations in protein-coding genes linked to disease
- Performed on: a blood/saliva sample, or an embryo biopsy during IVF
- Best suited for: carriers, recurrent loss & suspected genetic conditions
- Goal: identify healthy, unaffected embryos or guide treatment
- Delivered with: personalised genetic counselling
- Is This Test Right for You?
Who Should Consider Whole Exome Sequencing
WES is most often recommended for parents and couples in one of these situations.
Known Carrier Status
Either partner carries a gene linked to a known genetic abnormality or disorder.
Recurrent Miscarriage
A history of repeated pregnancy loss that may be linked to an underlying genetic cause.
Suspected Genetic Condition
A known or suspected inherited disorder in the family that warrants deeper investigation.
Couples Undergoing IVF
Parents who want embryos screened for genetic disorders before transfer for added confidence.
- How It Works
The WES Process at Life IVF Multan
A straightforward procedure with transformative diagnostic impact.
Sample Collection
A few drops of blood or saliva are collected from parents — or, during IVF, a small number of cells are carefully biopsied from the embryo.
DNA Sequencing
High-precision sequencing technology analyzes the exome — the protein-coding regions of the genome most likely to carry disease-linked mutations.
Genetic Interpretation
Our genetic experts analyze the results, focusing on potential health risks, carrier status, and inherited conditions relevant to you and your family.
Embryo Classification (During IVF)
When performed on embryos, results classify each one as affected, carrier, or healthy — so only the healthiest embryos are frozen or used for transfer.
Personalized Consultation
Your specialist walks you through what the results mean for your baby's health, your carrier status, and the most appropriate treatment or reproductive plan going forward.
- COMMON QUESTIONS
Frequently Asked Questions
WES is a genetic test that examines the protein-coding regions of your DNA — the areas most likely to carry mutations associated with disease.
It helps identify the genetic cause of unexplained or inherited conditions, providing answers when routine tests fall short and supporting accurate diagnosis, treatment planning, and family counselling.
A blood or saliva sample is collected from parents, or an embryo biopsy is taken during IVF. The protein-coding regions are then sequenced and analyzed by our genetic specialists.
Anyone carrying a gene linked to a genetic abnormality, with a history of recurrent miscarriage, or with a known or suspected genetic condition in the family.
WES can detect variants linked to rare inherited disorders, developmental and neurological conditions, metabolic or skeletal disorders, congenital anomalies, and certain fertility-related genetic issues.
Yes, whole exome sequencing is a simple, safe procedure whether performed on a parental sample or an embryo biopsy.
For parents (blood or saliva samples), results are typically available within 3–6 weeks. For embryos tested during IVF, results may take 4–6 weeks due to the biopsy, sequencing, and detailed analysis involved.
Cost depends on the complexity of the sample and the genetic condition being investigated. Our team provides a full, itemised estimate during your consultation.